Bioactive Small Molecules
Medchemexpress LLC TGFBI protein, human (HEK293, His) | >80.0% | 10 UG
Recombinant human transforming growth factor-beta-induced protein (TGFBI) produced in HEK293 cells and supplied as a solution with a C-terminal His tag. Intended for research use in studies of cell adhesion, extracellular matrix interactions, and biochemical characterization. Purity is stated as greater than 80% by reducing SDS-PAGE.
- Expressed in HEK293 cells for human-like post-translational modifications.
- C-terminal His tag enables purification and detection.
- Supplied as a solution ready for downstream assays.
- Purity >80% as determined by reducing SDS-PAGE.
- Suitable for studies of cell adhesion and extracellular matrix interactions.
Medchemexpress LLC HY-10968 5mg Medchemexpress, CYM5442 CAS:1094042-01-9 Purity:>98%
Medchemexpress, HY-10968 5mg CYM5442 CAS:1094042-01-9 CYM5442 is a potent, highly-selective and orally active sphingosine 1-phosphate (S1P1) receptor agonist with an EC50 of 1.35 nM. CYM5442 is inactive against S1P2, S1P3, S1P4, and S1P5. CYM5442 activates S1P1-dependent p42/p44-MAPK phosphorylation. CYM5442 exerts retinal neuroprotection. CYM5442 can easily penetrate the central nervous system (CNS). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Cayman Chemical MF766, Purity: ≥95%, CAS: 1050656-06-8, 25 mg
An EP4 receptor antagonist (Ki = 0.23 nM); selective for EP4 over DP1 (Ki = 1,648 nM) as well as EP1, EP2, EP3, CRTH2/DP2, IP, TP, and FP recetors (Kis = >6,000 nM for all); inhibits PGE2-induced cAMP accumulation in HEK293 cells (IC50 = 1.3 nM); reverses PGE2-induced decreases in IFN-γ production in IL-2-stimulated primary human natural killer cells at 312.5 and 1,250 nM; reduces paw edema in a rat model of adjuvant-induced arthritis; inhibits tumor growth in a CT26 murine colon cancer model at 30 mg/kg
Chemglass Life Sciences Flask Support Ring, Cork, 140 mm OD x 85 mm ID for Round-Bottom Flasks
Cork flask support ring designed to stabilize and cushion round-bottom flasks during routine laboratory operations. The dense cork construction provides a non-abrasive seating surface that helps protect glassware and maintain steady support on benchtops or lab stands.
- Outer diameter: 140 mm
- Inner diameter: 85 mm
- Material: cork
- Provides cushioned, non-abrasive support for round-bottom flasks
- Sold individually
Medchemexpress LLC HY-134205A 5mg Medchemexpress, CBR-470-1 CAS:2416095-06-0 Purity:>98%
Medchemexpress, HY-134205A 5mg CBR-470-1 CAS:2416095-06-0 CBR-470-1 is an inhibitor of the glycolytic enzyme phosphoglycerate kinase 1 (PGK1). CBR-470-1 is also a non-covalent Nrf2 activator. CBR-470-1 protects SH-SY5Y neuronal cells against MPP+-induced cytotoxicity through activation of the Keap1-Nrf2 cascade. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
TARGETMOL CHEMICALS INC RAC-BELINOSTAT 50MG
Also available in 5 mg 10 mg 25 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Rac-Belinostat (PX-105684) is a novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity. Belinostat targets HDAC enzymes thereby inhibiting tumor cell proliferation inducing apoptosis promoting cellular differentiation and inhibiting angiogenesis. This agent may sensitize drug-resistant tumor cells to other antineoplastic agents possibly through a mechanism involving the down-regulation of thymidylate synthase. purity: 99%
TARGETMOL CHEMICALS INC SY-5609 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. SY-5609 is a selective and noncovalent inhibitor of CDK7(KD = 0.065 nM) with antitumor activity and inhibits apoptosis. purity: 99%
Cayman Chemical 9(Z)-Pentacosene, Purity: ≥95%, CAS: 51865-00-0, 5 mg
A cuticular hydrocarbon and insect sex hormone; found in the cuticle of female F. canicularis flies and is an attractant to males in a trap assay; a contact sex hormone in scarab beetles and locust borers that is more abundant in females than males; elicits arrestment, alignment, and mounting by males of both species in mating assays, but only elicits copulation by the locust borer; produced by the orchid O. exaltata and by C. cunicularius, a pollinator of O. exaltata
Medchemexpress LLC Pegsebrenatide | 2243292-26-2 | 95.5% | 1 MG
Pegsebrenatide (NLY01) is a blood-brain barrier-penetrant GLP-1R agonist. It alleviates retinal inflammation and neuronal death, delays onset and reduces disease severity in experimental autoimmune encephalomyelitis, and exerts neuroprotective effects in Parkinson's disease models by preventing microglia-mediated conversion of astrocytes to the A1 neurotoxic phenotype. It is useful for research on glaucoma, Parkinson's disease, and multiple sclerosis.
- Blood-brain barrier-penetrant GLP-1R agonist
- Alleviates retinal inflammation and neuron death
- Delays onset and reduces disease severity in experimental autoimmune encephalomyelitis
- Inhibits formation of A1 reactive astrocytes
- Reduces loss of retinal ganglion cells and dopaminergic neurons
- Exerts neuroprotective effects in Parkinson's disease models
- Useful for research on glaucoma, Parkinson's disease, and multiple sclerosis
Medchemexpress LLC Glucosamine (hydrochloride) | 66-84-2 | 215.63 | 25 G
Glucosamine hydrochloride is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, used as a dietary supplement. It is also a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, and when administered exogenously, it exerts pharmacological effects on osteoarthritic cartilage and chondrocytes.
- Exhibits dose-dependent DPPH antioxidant activity.
- Short-term treatment inhibits HIF-1α at the protein level.
- Decreases renal expression of α-smooth muscle actin, collagen I, and fibronectin.
- Purity 98.0%.
- Appearance is solid.
- Color is white to off-white.
- Initial source includes animals, microorganisms, and endogenous metabolite.
Medchemexpress LLC Animal-Free IL-22 M 10ug
Recombinant animal-free mouse interleukin-22 (IL-22) with a C-terminal His tag, expressed in E. coli and supplied for cell culture applications. The product corresponds to mouse IL-22 (sequence L34-V179, accession Q9JJY9), has an approximate molecular weight of 17 kDa by SDS-PAGE, and is provided at ~95% purity. Available in small research sizes (2 μg, 10 μg, 50 μg).
- Animal-free recombinant formulation suitable for cell culture use.
- C-terminal His tag enables detection and affinity purification.
- Expressed in E. coli for consistent, scalable production.
- Approximately 17 kDa molecular weight by SDS-PAGE.
- High purity (~95%) for reproducible experimental results.
- Available in small, convenient microgram pack sizes for screening.
Cayman Chemical L-Carnitine-d3 (chloride), Purity: ≥99% deuterated forms (d1-d3), CAS: 350818-62-1, 5 mg
An internal standard for the quantification of L-carnitine by GC- or LC-MS
Selleck Chemical LLC Broussonetiae Fructus Extract E3096-5MG
Broussonetiae Fructus Extract is obtained from Fructus Broussonetiae significantly increases the expression of immunoglobulin-binding protein decreases expression levels of PKR-like endoplasmic reticulum kinase and C/EBP homologous protein and substantially improves learning memory and spatial recognition dysfunction in Alzheimer s disease rats
Cayman Chemical N-desmethyl Sildenafil, Purity: ≥98%, CAS: 139755-82-1, 5 mg
A major metabolite of sildenafil; formed via oxidative metabolism of sildenafil by CYP3A4, CYP3A5, and CYP3A7
c1nc2cccc(F)c2c(=O)n1-c1ccccc1 | 1g | 410712257](https://assets.fishersci.com/TFS-Assets/CCG/product-images/NC2230803.JPG-250.jpg)
eMolecules 870281-82-6 | IDELALISIB | AstaTech | MFCD19443647 | 415.432 | C22H18FN7O | 95.000 | CC[C@H](Nc1ncnc2[nH]cnc12)c1nc2cccc(F)c2c(=O)n1-c1ccccc1 | 1g | 410712257
IDELALISIB | AstaTech | 870281-82-6 | MFCD19443647 | 415.432 | C22H18FN7O | 95.000 | CC[C@H](Nc1ncnc2[nH]cnc12)c1nc2cccc(F)c2c(=O)n1-c1ccccc1 | 1g | 410712257